Symptoms and Diagnosis
Can STDs Alter Your Sense of Taste or Smell? Bizarre Symptoms Revealed
Mar 19, 2025
Sexually transmitted diseases (STDs) are often associated with genital symptoms, discharge, or pain, but did you know that some infections can affect your sense of taste or smell? While uncommon, neurological complications from certain STDs—such as syphilis and HPV-related throat infections—can lead to changes in taste perception or even loss of smell.
✔ Syphilis can damage cranial nerves, leading to altered taste and smell.
✔ HPV-related throat cancer may present with early taste bud changes or persistent throat discomfort.
✔ HIV and other infections can cause chronic inflammation affecting sensory perception.
This article explores how STDs can impact taste and smell, what the science says about these unusual symptoms, and when getting tested is crucial for early detection.
1. Syphilis and Cranial Nerve Damage: When Taste and Smell Are Affected
How Syphilis Causes Sensory Changes
Syphilis, caused by Treponema pallidum, progresses in stages, with secondary syphilis affecting the nervous system in some cases.
✔ Cranial nerve involvement can lead to loss of taste (ageusia) or distorted smell (parosmia).
✔ Meningitis-like symptoms in secondary syphilis can inflame nerves responsible for taste and smell.
✔ Untreated syphilis can progress to neurosyphilis, causing long-term nerve damage.
Scientific Evidence: CDC Case Reports on Syphilis and Sensory Loss
According to the Centers for Disease Control and Prevention (CDC), several reported cases of syphilis-induced cranial nerve damage have resulted in loss of taste, smell distortions, and even partial facial paralysis (CDC - Syphilis).
✔ Patients with secondary syphilis have reported sudden inability to taste bitter or sour foods.
✔ Some cases included altered smell perception, with patients describing "phantom odors" or a complete loss of smell.
✔ Symptoms often improved after antibiotic treatment, highlighting the importance of early STD testing.
Key Takeaway: If you experience unexplained changes in taste or smell, testing for syphilis should be considered—especially if you have other flu-like symptoms or a history of unprotected sex.
2. HPV and Throat Cancer: How It Affects Taste Perception
HPV’s Role in Oropharyngeal Cancer
Human papillomavirus (HPV) is best known for causing genital warts and cervical cancer, but certain strains (like HPV-16) are also linked to throat cancer.
✔ HPV-related throat cancer affects the base of the tongue, tonsils, and pharynx.
✔ Early symptoms may include changes in taste, chronic sore throat, and difficulty swallowing.
✔ HPV infections in the throat can inflame taste buds, altering perception of flavors.
Early Warning Signs of HPV-Related Taste Disturbances
✔ Persistent sore throat without an obvious cause.
✔ Loss of sensitivity to bitter or metallic tastes.
✔ Chronic dry mouth or burning sensation in the throat.
Key Takeaway: If you notice long-term taste changes along with a persistent sore throat, HPV screening may be necessary. The CDC recommends HPV vaccination to prevent throat infections and related cancers (CDC - HPV & Cancer).
3. Other STDs That Can Affect Taste and Smell
✔ HIV – Chronic inflammation and opportunistic infections can lead to loss of taste and smell distortions.
✔ Gonorrhea & Chlamydia – Untreated oral infections can cause throat inflammation, metallic taste, and discomfort.
✔ Herpes (HSV-1) – Recurring oral infections may irritate taste buds, causing sensitivity or altered flavors.
When Should You Get Tested?
If you experience unexplained changes in taste or smell, along with:
✔ Persistent sore throat or difficulty swallowing.
✔ Flu-like symptoms (fatigue, fever, swollen lymph nodes).
✔ Unusual rashes or mouth ulcers.
✔ A history of recent unprotected sex.
For fast and confidential STD testing, visit STDCheck, our trusted partner, for comprehensive screenings and rapid results.
4. How to Protect Yourself from STD-Related Sensory Changes
✔ Practice Safe Sex – Use condoms and dental dams to reduce oral STD risk.
✔ Get Vaccinated for HPV – The HPV vaccine significantly lowers cancer risk.
✔ Schedule Routine STD Testing – Regular screening prevents long-term complications.
✔ Seek Early Treatment – Treating infections early reduces nerve damage risk.
Conclusion
Though rare, STDs can impact your sense of taste and smell, particularly when they affect the nervous system or cause chronic inflammation.
✔ Syphilis can damage cranial nerves, leading to altered taste and smell perception.
✔ HPV-related throat infections may cause changes in taste as an early symptom.
✔ Other infections like HIV, gonorrhea, and herpes can also affect sensory functions.
✔ Regular STD screening is essential for detecting infections before they cause long-term effects.

Dr. Michael Thompson
Dr. Michael Thompson is an expert in sexually transmitted diseases with extensive clinical and research experience. He leads campaigns advocating for early diagnosis and prevention of diseases like HIV and gonorrhea. He collaborates with local organizations to educate both youth and adults about sexual health.